The new study, conducted by researchers at Duke-NUS, reveals Active-DHA transported by MFSD2a found at the blood brain barrier plays a physiological role in both brain growth and health during brain development. LPC-DHA or ‘Active-DHA’ is a natural form of docosahexaenoic acid (DHA) that is attached to a lysophosphatidylcholine (LPC).
Mediacorp Channel 8 News, August 16, 2018
PLOS Biology, August 2018
Springer Nature, July 2018
The major facilitator superfamily domain-containing protein 2A (MFSD2A) is a constituent of the blood-brain barrier and functions to transport lysophosphatidylcholines (LPCs) into the central nervous system.
J Biol Chem, 2016. 291(18): p. 9383-94
Nat Genet, 2015. 47(7): p. 809-13
Nature, 2014. 509(7501): p. 503-6